Total THC2 Cell-Based Colorimetric ELISA Kit
-KA3861C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
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Total THC2 Cell-Based Colorimetric ELISA Kit
KA3861C
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抗原&靶点信息
基因名称:
MASTL
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别名:
Serine/threonine-protein kinase greatwall ;
GW ;
GWL ;
hGWL ;
Microtubule-associated serine/threonine-protein kinase-like ;
MAST-L ;
GW ;
GWL ;
hGWL ;
Microtubule-associated serine/threonine-protein kinase-like ;
MAST-L ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) [MIM:188000]. Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased bleeding and decreased ability for clotting.,function:Putative serine/threonine kinase which may be involved in megakaryocyte differentiation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,
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功能:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
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细胞定位:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves to the cleavage furrow. .
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