STEAP2

Metalloreductase STEAP2 ;
Prostate cancer-associated protein 1 ;
Protein up-regulated in metastatic prostate cancer ;
PUMPCn ;
Six-transmembrane epithelial antigen of prostate 2 ;
SixTransMembrane protein of prostate 1 ;

cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.,

transition metal ion transport, generation of precursor metabolites and energy, ion transport, cation transport, iron ion transport, exocytosis, post-Golgi vesicle-mediated transport, Golgi to plasma membrane transport, endocytosis,response to endogenous stimulus, response to hormone stimulus, response to organic substance, membrane invagination, di-, tri-valent inorganic cation transport, membrane organization, vesicle-mediated transport, electron transport chain, metal ion transport, secretion by cell, regulated secretory pathway, secretion, intracellular transport,Golgi vesicle transport, oxidation reduction,

Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.