Total MKP-3 Cell-Based Colorimetric ELISA Kit
-KA3773C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
DUSP6
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别名:
Dual specificity protein phosphatase 6 ;
EC 3.1.3.48 ;
Dual specificity protein phosphatase PYST1 ;
Mitogen-activated protein kinase phosphatase 3 ;
MAP kinase phosphatase 3 ;
MKP-3 ;
EC 3.1.3.48 ;
Dual specificity protein phosphatase PYST1 ;
Mitogen-activated protein kinase phosphatase 3 ;
MAP kinase phosphatase 3 ;
MKP-3 ;
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背景:
catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Inactivates MAP kinases. Has a specificity for the ERK family.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
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功能:
MAPKKK cascade, inactivation of MAPK activity, negative regulation of protein kinase activity, protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade,protein kinase cascade, dephosphorylation, regulation of phosphate metabolic process, negative regulation of kinase activity, regulation of phosphorylation, negative regulation of catalytic activity, regulation of MAP kinase activity,negative regulation of MAP kinase activity, regulation of kinase activity, negative regulation of molecular function,regulation of protein kinase activity, regulation of phosphorus metabolic process, regulation of transferase activity,negative regulation of transferase activity,
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细胞定位:
Cytoplasm .
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组织表达:
Expressed in keratinocytes (at protein level).
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信号通路
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