Total SYT Cell-Based Colorimetric ELISA Kit
-KA3749C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
SS18
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别名:
Protein SSXT ;
Protein SYT ;
Synovial sarcoma translocated to X chromosome protein ;
Protein SYT ;
Synovial sarcoma translocated to X chromosome protein ;
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背景:
disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,similarity:Belongs to the SS18 family.,tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.,
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功能:
microtubule cytoskeleton organization, cell morphogenesis, regulation of transcription, DNA-dependent, cytoskeleton organization, microtubule-based process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, intracellular signaling cascade, protein kinase cascade, cellular component morphogenesis, response to drug, regulation of transcription,ephrin receptor signaling pathway, regulation of RNA metabolic process,
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细胞定位:
Nucleus .
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组织表达:
Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
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信号通路
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