ZMYND11

Zinc finger MYND domain-containing protein 11 ;
Adenovirus 5 E1A-binding protein ;
Protein BS69 ;

function:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,

negative regulation of transcription from RNA polymerase II promoter, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell cycle, cell proliferation, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, negative regulation of gene expression, negative regulation of transcription,negative regulation of cellular biosynthetic process, regulation of transcription, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process,

Nucleus . Chromosome . Associates with chromatin and mitotic chromosomes. .

Ubiquitous.