Total MB67 Cell-Based Colorimetric ELISA Kit
-KA3737C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
NR1I3
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别名:
Nuclear receptor subfamily 1 group I member 3 ;
Constitutive activator of retinoid response ;
Constitutive active response ;
Constitutive androstane receptor ;
CAR ;
Orphan nuclear receptor MB67 ;
Constitutive activator of retinoid response ;
Constitutive active response ;
Constitutive androstane receptor ;
CAR ;
Orphan nuclear receptor MB67 ;
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背景:
domain:Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.,function:Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.,induction:By dexamethasone.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer of NR1I3 and RXR. Interacts with PSMC4.,tissue specificity:Predominantly expressed in liver.,
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功能:
transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
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细胞定位:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7. .
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组织表达:
Predominantly expressed in liver.
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