Total CaMKIIβ/γ Cell-Based Colorimetric ELISA Kit
-KA3719C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
CAMK2B/CAMK2G
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.,
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功能:
G1/S transition of mitotic cell cycle, mitotic cell cycle, peptide secretion, generation of a signal involved in cell-cell signaling, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, ion transport, cation transport, calcium ion transport, cell cycle, cell-cell signaling, hormone transport, regulation of hormone levels, di-, tri-valent inorganic cation transport, peptide transport, phosphorylation, cell cycle process, cell cycle phase, metal ion transport, peptide hormone secretion, insulin secretion, secretion by cell, protein amino acid autophosphorylation, hormone secretion, secretion, interphase, interphase of mitotic cell cycle,
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细胞定位:
Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .
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组织表达:
Expressed in skeletal muscle.
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信号通路
Cellular Processes >> Cell growth and death >> Necroptosis
Organismal Systems >> Endocrine system >> Insulin secretion
Organismal Systems >> Endocrine system >> Glucagon signaling pathway
Organismal Systems >> Endocrine system >> GnRH signaling pathway
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Organismal Systems >> Nervous system >> Cholinergic synapse
Organismal Systems >> Nervous system >> Dopaminergic synapse
Organismal Systems >> Nervous system >> Neurotrophin signaling pathway
Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: specific types >> Glioma
Human Diseases >> Neurodegenerative disease >> Parkinson disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> ErbB signaling pathway
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
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