FOXI1

Forkhead box protein I1 ;
Forkhead-related protein FKHL10 ;
Forkhead-related transcription factor 6 ;
FREAC-6 ;
Hepatocyte nuclear factor 3 forkhead homolog 3 ;
HFH-3 ;
HNF-3/fork-head homolog 3 ;

function:Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in kidney.,

transcription, regulation of transcription, DNA-dependent, sensory organ development, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, positive regulation of cellular biosynthetic process, ear morphogenesis, inner ear morphogenesis, ear development, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, embryonic organ morphogenesis, embryonic organ development,embryonic morphogenesis, inner ear development, positive regulation of nitrogen compound metabolic process,regulation of RNA metabolic process, positive regulation of RNA metabolic process,

Nucleus.

Expressed in kidney.