NCBP1

Nuclear cap-binding protein subunit 1 ;
80 kDa nuclear cap-binding protein ;
CBP80 ;
NCBP 80 kDa subunit ;

function:Involved in mediating U snRNA export from the nucleus. Binds to 5' capped mRNA.,similarity:Belongs to the NCBP1 family.,similarity:Contains 1 MIF4G domain.,subunit:Found in a U snRNA export complex with RNUXA/PHAX, CBP20, CBP80, RAN, XPO1 and m7G-capped RNA. Interaction with RNUXA/PHAX (By similarity). Heterodimer with NCBP2. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2, THOC4 and/or REFBP2.,

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, RNA splicing, via transesterification reactions,RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, spliceosomal snRNP biogenesis,nuclear mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, mRNA capping, mRNA cleavage,RNA processing, mRNA processing, RNA catabolic process, mRNA catabolic process, RNA localization, RNA export from nucleus, mRNA export from nucleus, regulation of translation, regulation of translational initiation, nucleocytoplasmic transport, RNA splicing, macromolecule catabolic process, RNA capping, positive regulation of macromolecule metabolic process, posttranscriptional regulation of gene expression, nucleobase, nucleoside, nucleotide and nucleic acid transport, mRNA metabolic process, ribonucleoprotein complex biogenesis, ribonucleoprotein complex assembly,regulation of mRNA 3'-end processing, positive regulation of mRNA 3'-end processing, regulation of cellular protein metabolic process, cellular macromolecular complex subunit organization, cellular macromolecular complex assembly,macromolecular complex subunit organization, cellular macromolecule catabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, intracellular transport, nucleic acid transport,RNA transport, regulation of mRNA processing, positive regulation of mRNA processing, mRNA transport, nuclear export, nuclear transport, positive regulation of nitrogen compound metabolic process, establishment of RNA localization, regulation of RNA metabolic process, positive regulation of RNA metabolic process, macromolecular complex assembly,

Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .