Total ER81 Cell-Based Colorimetric ELISA Kit
-KA3623C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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Total ER81 Cell-Based Colorimetric ELISA Kit
KA3623C
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抗原&靶点信息
基因名称:
ETV1
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别名:
ETS translocation variant 1 ;
Ets-related protein 81 ;
Ets-related protein 81 ;
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背景:
disease:A chromosomal aberration involving ETV1 is a cause of Ewing sarcoma [MIM:133450]. Translocation t(7;22)(p22;q12) with EWS.,function:Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.,PTM:Sumoylated.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,tissue specificity:Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.,
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功能:
transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, RNA biosynthetic process, regulation of transcription, regulation of RNA metabolic process,
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细胞定位:
Nucleus .
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组织表达:
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
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