Total TIS11D Cell-Based Colorimetric ELISA Kit
-KA3614C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
ZFP36L2
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别名:
Zinc finger protein 36, C3H1 type-like 2 ;
ZFP36-like 2 ;
Butyrate response factor 2 ;
EGF-response factor 2 ;
ERF-2 ;
Protein TIS11D ;
ZFP36-like 2 ;
Butyrate response factor 2 ;
EGF-response factor 2 ;
ERF-2 ;
Protein TIS11D ;
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背景:
function:Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.,similarity:Contains 2 C3H1-type zinc fingers.,
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功能:
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, RNA catabolic process, mRNA catabolic process, cell proliferation, macromolecule catabolic process,posttranscriptional regulation of gene expression, mRNA metabolic process, regulation of RNA stability, regulation of mRNA stability, cellular macromolecule catabolic process, regulation of RNA metabolic process,
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细胞定位:
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. .
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组织表达:
Expressed mainly in the basal epidermal layer, weakly in the suprabasal epidermal layers (PubMed:27182009). Expressed in epidermal keratinocytes (at protein level) (PubMed:27182009).
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