Total Recoverin Cell-Based Colorimetric ELISA Kit
-KA3591C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
RCVRN
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别名:
Recoverin ;
Cancer-associated retinopathy protein ;
Protein CAR ;
Cancer-associated retinopathy protein ;
Protein CAR ;
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背景:
disease:Identified as the antigen in cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.,function:Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.,miscellaneous:Binds two calcium ions; one with high affinity, the other with low affinity.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,tissue specificity:Retina and pineal gland.,
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功能:
sensory perception, visual perception, phototransduction, response to radiation, response to light stimulus, detection of external stimulus, detection of abiotic stimulus, detection of light stimulus, response to abiotic stimulus, regulation of metal ion transport, regulation of ion transport, neurological system process, cognition, sensory perception of light stimulus, detection of stimulus, regulation of calcium ion transport,
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细胞定位:
Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Photoreceptor outer segment membrane ; Lipid-anchor ; Cytoplasmic side . Perikaryon . Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (By similarity). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity). .
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组织表达:
Retina and pineal gland.
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