EGR2

function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.,induction:By growth factors.,similarity:Belongs to the EGR C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

negative regulation of transcription from RNA polymerase II promoter, cell activation, immune system development,leukocyte differentiation, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, behavior, learning or memory, negative regulation of biosynthetic process, positive regulation of biosynthetic process, response to organic substance, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression, negative regulation of gene expression, negative regulation of transcription, hemopoiesis, lymphocyte differentiation, T cell differentiation, negative regulation of cellular biosynthetic process, positive regulation of cellular biosynthetic process,regulation of neurological system process, T cell activation, regulation of system process, leukocyte activation,regulation of transcription, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, lymphocyte activation, regulation of synaptic plasticity, regulation of neuronal synaptic plasticity, regulation of long-term neuronal synaptic plasticity,hemopoietic or lymphoid organ development, regulation of synaptic transmission, neurological system process,cognition, negative regulation of nitrogen compound metabolic process, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, positive regulation of RNA metabolic process, response to protein stimulus, regulation of transmission of nerve impulse,

Nucleus . Cytoplasm .

Detected in neutrophils (at protein level).