Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

HAVCR1

Hepatitis A virus cellular receptor 1

HAVCR1 ;
KIM1 ;
TIM1 ;
TIMD1 ;
Hepatitis A virus cellular receptor 1 ;
HAVcr-1 ;
Kidney injury molecule 1 ;
KIM-1 ;
T-cell immunoglobulin and mucin domain-containing protein 1 ;
TIMD-1 ;
T-cell membrane protein 1 ;
TIM-1 ;
TIM

function:May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity) . In case of human hepatitis A virus (HHAV) infection , functions as a cell-surface receptor for the virus. ,polymorphism:HHAV seropositivity protects against atopy in individuals with the variants Met-Thr-Thr-Val-Pro-157 ins and Met-Thr-Thr-Thr-Val-Pro-157 ins. Modernisation has led to a reduction in HAV seroprevalence and thus , may be , to an increase of expression of atopy , such as asthma , allergic rhinitis and atopic dermatitis. Allelic variation does not affect HAV-infection rates in Caucasians , Asians and African Americans. ,similarity:Belongs to the immunoglobulin superfamily. TIM family. ,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain. ,tissue specificity:Widely expressed , with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. ,

Cell membrane ; Single-pass type I membrane protein .