Total Fes Cell-Based Colorimetric ELISA Kit
-KA3526C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
Fes Rabbit pAb
YT1693
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Primary Antibodies
Fes Mouse mAb
YM0263
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ELISA Kits
Total Fes Cell-Based Colorimetric ELISA Kit
KA3526C
预览→
抗原&靶点信息
基因名称:
FES
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别名:
Tyrosine-protein kinase Fes/Fps ;
Feline sarcoma/Fujinami avian sarcoma oncogene homolog ;
Proto-oncogene c-Fes ;
Proto-oncogene c-Fps ;
p93c-fes ;
Feline sarcoma/Fujinami avian sarcoma oncogene homolog ;
Proto-oncogene c-Fes ;
Proto-oncogene c-Fps ;
p93c-fes ;
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背景:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.,similarity:Contains 1 FCH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,
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功能:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell proliferation,phosphorylation, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification,
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细胞定位:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.
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组织表达:
Widely expressed. Detected in adult colon epithelium (at protein level) (PubMed:16455651, PubMed:19051325). Expressed in melanocytes (at protein level) (PubMed:28463229).
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