Total Six3/6 Cell-Based Colorimetric ELISA Kit
-KA3512C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
SIX6
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别名:
Homeobox protein SIX6 ;
Homeodomain protein OPTX2 ;
Optic homeobox 2 ;
Sine oculis homeobox homolog 6 ;
Homeodomain protein OPTX2 ;
Optic homeobox 2 ;
Sine oculis homeobox homolog 6 ;
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背景:
disease:Defects in SIX6 are the cause of microphthalmia isolated with cataract type 2 (MCOPCT2) [MIM:212550]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.,function:May be involved in eye development.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.,
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功能:
regulation of transcription, DNA-dependent, sensory perception, visual perception, regulation of transcription,neurological system process, cognition, sensory perception of light stimulus, regulation of RNA metabolic process,
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细胞定位:
Nucleus .
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组织表达:
Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.
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