Total FIR Cell-Based Colorimetric ELISA Kit
-KA3501C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
FARP2
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别名:
FERM, RhoGEF and pleckstrin domain-containing protein 2 ;
FERM domain including RhoGEF ;
FIR ;
Pleckstrin homology domain-containing family C member 3 ;
PH domain-containing family C member 3 ;
FERM domain including RhoGEF ;
FIR ;
Pleckstrin homology domain-containing family C member 3 ;
PH domain-containing family C member 3 ;
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背景:
function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,
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功能:
intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, neuron remodeling, Rac protein signal transduction, developmental maturation, neuron differentiation, regulation of Rho protein signal transduction, neuron maturation, regulation of Ras protein signal transduction, cell maturation, neuron development, regulation of small GTPase mediated signal transduction,
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