Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

ANGPT1

Angiopoietin-1

ANGPT1 ;
KIAA0003 ;
Angiopoietin-1 ;
ANG-1

function:Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. ,miscellaneous:It may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart. ,online information:Angiopoietin entry ,PTM:Glycosylated. ,similarity:Contains 1 fibrinogen C-terminal domain. ,

angiogenesis , ovarian follicle development , blood vessel development , response to hypoxia , vasculature development ,reproductive developmental process , protein complex assembly , cell surface receptor linked signal transduction ,enzyme linked receptor protein signaling pathway , transmembrane receptor protein tyrosine kinase signaling pathway , sex differentiation , response to nutrient , gonad development , female gonad development , response to endogenous stimulus , response to hormone stimulus , response to extracellular stimulus , response to organic substance , ovulation cycle process , regeneration , organ regeneration , response to nutrient levels , multicellular organism reproduction , response to vitamin , response to vitamin B3 , ovulation cycle , response to estrogen stimulus ,macromolecular complex subunit organization , development of primary sexual characteristics , regulation of anti-apoptosis , positive regulation of anti-apoptosis , development of primary female sexual characteristics , female sex differentiation , rhythmic process , blood vessel morphogenesis , response to steroid hormone stimulus , reproductive structure development , reproductive process in a multicellular organism , protein oligomerization , protein homooligomerization , macromolecular complex assembly , protein complex biogenesis , response to oxygen levels ,

Secreted.