Total Zic1/2/3 Cell-Based Colorimetric ELISA Kit
-KA3474C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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Total Zic1/2/3 Cell-Based Colorimetric ELISA Kit
KA3474C
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抗原&靶点信息
基因名称:
ZIC1/ZIC2/ZIC3
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背景:
function:May play a role in cerebellar development.,similarity:Belongs to the GLI C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,tissue specificity:CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.,
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功能:
pattern specification process, sensory organ development, behavior, regulation of smoothened signaling pathway, ear morphogenesis, inner ear morphogenesis, ear development, embryonic organ morphogenesis, embryonic organ development, embryonic morphogenesis, inner ear development,
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细胞定位:
Nucleus. Cytoplasm . Localizes in the cytoplasm in presence of MDFIC overexpression. .
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组织表达:
CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.
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