Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CSF1

Macrophage colony-stimulating factor 1

CSF1 ;
Macrophage colony-stimulating factor 1 ;
CSF-1 ;
M-CSF ;
MCSF ;
Lanimostim

function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production , differentiation , and function of 2 related white cell populations of the blood , the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses , bone metabolism , lipoproteins clearance , fertility and pregnancy. ,PTM:Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. ,PTM:Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated. ,subunit:Homodimer or heterodimer; disulfide-linked. ,

cell activation , tissue homeostasis , regulation of cell-matrix adhesion , positive regulation of cell-matrix adhesion ,myeloid leukocyte activation , immune system development , leukocyte differentiation , myeloid leukocyte differentiation ,regulation of myeloid leukocyte differentiation , positive regulation of myeloid leukocyte differentiation , reproductive developmental process , cell proliferation , positive regulation of cell proliferation , positive regulation of signal transduction , positive regulation of macromolecule metabolic process , positive regulation of gene expression , positive regulation of cell communication , regulation of foam cell differentiation , positive regulation of foam cell differentiation ,regulation of cell-substrate adhesion , positive regulation of cell-substrate adhesion , regulation of phosphate metabolic process , hemopoiesis , myeloid cell differentiation , regulation of cell adhesion , macrophage differentiation ,regulation of ossification , regulation of cell migration , positive regulation of cell migration , regulation of cellular protein metabolic process , positive regulation of cellular protein metabolic process , regulation of mononuclear cell proliferation , positive regulation of mononuclear cell proliferation , positive regulation of kinase activity , regulation of growth , regulation of locomotion , regulation of multicellular organism growth , positive regulation of locomotion ,positive regulation of multicellular organism growth , monocyte activation , regulation of cell proliferation , regulation of phosphorylation , odontogenesis , regulation of odontogenesis , positive regulation of odontogenesis , regulation of odontogenesis of dentine-containing tooth , positive regulation of odontogenesis of dentine-containing tooth ,homeostatic process , positive regulation of catalytic activity , regulation of kinase activity , positive regulation of molecular function , leukocyte activation , positive regulation of cell differentiation , regulation of myeloid cell differentiation , positive regulation of myeloid cell differentiation , regulation of macrophage differentiation , positive regulation of macrophage differentiation , regulation of monocyte differentiation , positive regulation of monocyte differentiation , regulation of osteoclast differentiation , positive regulation of osteoclast differentiation , positive regulation of cell adhesion , regulation of protein kinase activity , positive regulation of protein kinase activity , positive regulation of growth , regulation of Ras protein signal transduction , positive regulation of Ras protein signal transduction , hemopoietic or lymphoid organ development , multicellular organismal homeostasis , homeostasis of number of cells , homeostasis of number of cells within a tissue , regulation of small GTPase mediated signal transduction , positive regulation of small GTPase mediated signal transduction , positive regulation of developmental process , regulation of phosphorus metabolic process , positive regulation of multicellular organismal process , positive regulation of protein metabolic process , regulation of cell motion , positive regulation of cell motion , regulation of transferase activity , positive regulation of transferase activity , anatomical structure homeostasis , regulation of leukocyte proliferation , positive regulation of leukocyte proliferation ,

Cell membrane ; Single-pass type I membrane protein .; [Processed macrophage colony-stimulating factor 1]: Secreted , extracellular space.