Total XRCC3 Cell-Based Colorimetric ELISA Kit
-KA3434C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
XRCC3
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别名:
DNA repair protein XRCC3 ;
X-ray repair cross-complementing protein 3 ;
X-ray repair cross-complementing protein 3 ;
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背景:
disease:Met-241 is associated with the development of cutaneous malignant melanoma.,function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.,
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功能:
DNA metabolic process, DNA repair, DNA recombination, response to DNA damage stimulus, cellular response to stress,
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细胞定位:
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair.
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