caution:It is uncertain whether Met-1 or Met-5 is the initiator. ,function:Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. ,induction:By viral infections or double stranded RNA. ,online information:Interleukin-28 entry ,similarity:Belongs to the IL-28/IL-29 family. ,
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