Total VEGF-B Cell-Based Colorimetric ELISA Kit
-KA3427C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
VEGFB
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别名:
Vascular endothelial growth factor B ;
VEGF-B ;
VEGF-related factor ;
VRF ;
VEGF-B ;
VEGF-related factor ;
VRF ;
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背景:
alternative products:Additional isoforms seem to exist,function:Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.,PTM:VEGF-B186 is O-glycosylated.,similarity:Belongs to the PDGF/VEGF growth factor family.,subcellular location:Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.,subunit:Homodimer; disulfide-linked. Can also form heterodimer with VEGF.,tissue specificity:Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.,
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功能:
regulation of cell growth, cell proliferation, positive regulation of cell proliferation, regulation of growth, regulation of cell proliferation, regulation of cell division, positive regulation of cell division,
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细胞定位:
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
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组织表达:
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Organismal Systems >> Endocrine system >> Relaxin signaling pathway
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
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