Total TIMP-2 Cell-Based Colorimetric ELISA Kit
-KA3398C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
TIMP2
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别名:
Metalloproteinase inhibitor 2 ;
CSC-21K ;
Tissue inhibitor of metalloproteinases 2 ;
TIMP-2 ;
CSC-21K ;
Tissue inhibitor of metalloproteinases 2 ;
TIMP-2 ;
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背景:
function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.,PTM:The activity of TIMP2 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,
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功能:
regulation of nucleotide metabolic process, negative regulation of cell proliferation, regulation of protein kinase cascade, regulation of cyclic nucleotide metabolic process, regulation of cAMP metabolic process, regulation of cell proliferation, regulation of MAPKKK cascade, regulation of neuron differentiation, regulation of neurogenesis,regulation of nervous system development, regulation of cell development,
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细胞定位:
Secreted.
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