RARB

Retinoic acid receptor beta ;
RAR-beta ;
HBV-activated protein ;
Nuclear receptor subfamily 1 group B member 2 ;
RAR-epsilon ;

domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,

negative regulation of transcription from RNA polymerase II promoter, eye development, urogenital system development, metanephros development, ureteric bud development, kidney development, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, sensory organ development, heart development, muscle organ development, negative regulation of cell proliferation, negative regulation of biosynthetic process, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression,negative regulation of gene expression, regulation of cell death, positive regulation of cell death, striated muscle tissue development, negative regulation of transcription, embryonic limb morphogenesis, negative regulation of cellular biosynthetic process, positive regulation of cellular biosynthetic process, cardiac cell differentiation, appendage morphogenesis, limb morphogenesis, embryonic appendage morphogenesis, embryonic hindlimb morphogenesis,hindlimb morphogenesis, tube development, regulation of cell proliferation, muscle cell differentiation, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, regulation of transcription, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, embryonic eye morphogenesis, embryonic organ morphogenesis, embryonic organ development, eye morphogenesis, embryonic morphogenesis, appendage development, cardiac muscle tissue development, striated muscle cell differentiation,negative regulation of nitrogen compound metabolic process, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, positive regulation of RNA metabolic process, cardiac muscle cell differentiation, ventricular cardiac muscle cell differentiation, limb development,muscle tissue development,

Nucleus . Cytoplasm .; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.

Expressed in aortic endothelial cells (at protein level).