Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CCL3

C-C motif chemokine 3

CCL3 ;
G0S19-1 ;
MIP1A ;
SCYA3 ;
C-C motif chemokine 3 ;
G0/G1 switch regulatory protein 19-1 ;
Macrophage inflammatory protein 1-alpha ;
MIP-1-alpha ;
PAT 464.1 ;
SIS-beta ;
Small-inducible cytokine A3 ;
Tonsillar lymphocyte LD78 alpha protein

function:Monokine with inflammatory and chemokinetic properties. Binds to CCR1 , CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1 , HIV-2 , and simian immunodeficiency virus (SIV) . ,induction:By TPA or PHA (TPA = 12-O-tetradecanoyl phorbol-13 acetate (tumor promoter) ; PHA = phytohemagglutinin (T-cell mitogen) ) . ,online information:Macrophage inflammatory protein entry ,PTM:N-terminal processed form LD78-alpha (4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. ,similarity:Belongs to the intercrine beta (chemokine CC) family. ,subunit:Self-associates. Also heterodimer of MIP-1-alpha (4-69) and MIP-1-beta (3-69) . ,

cellular ion homeostasis , cellular calcium ion homeostasis , cellular metal ion homeostasis , exocytosis , cell motion ,chemotaxis , defense response , inflammatory response , immune response , cytoskeleton organization , cell surface receptor linked signal transduction , G-protein coupled receptor protein signaling pathway , cell-cell signaling , behavior ,locomotory behavior , response to wounding , vesicle-mediated transport , cellular homeostasis , cellular cation homeostasis , cellular di- , tri-valent inorganic cation homeostasis , secretion by cell , taxis , homeostatic process ,regulation of viral genome replication , secretion , chemical homeostasis , regulation of viral reproduction , ion homeostasis , metal ion homeostasis , di- , tri-valent inorganic cation homeostasis , calcium ion homeostasis , cation homeostasis , cellular chemical homeostasis ,

Secreted.