Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CXCL11 ITAC SCYB11 SCYB9B

C-X-C motif chemokine 11

CXCL11 ;
ITAC ;
SCYB11 ;
SCYB9B ;
C-X-C motif chemokine 11 ;
Beta-R1 ;
H174 ;
Interferon gamma-inducible protein 9 ;
IP-9 ;
Interferon-inducible T-cell alpha chemoattractant ;
I-TAC ;
Small-inducible cytokine B11

disease:Expressed in a variety of skin disorders , including allergic contact dermatitis , lichen planus and mycosis fungoides. ,function:Chemotactic for interleukin-activated T-cells but not unstimulated T-cells , neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. ,induction:By interferon gamma and interferon beta. Induction by IFN-gamma is enhanced by TNF-alpha in monocytes , dermal fibroblasts and endothelial cells , and by IL-1 in astrocytes. ,mass spectrometry: PubMed:10233762 ,online information:CXCL11 entry ,similarity:Belongs to the intercrine alpha (chemokine CxC) family. ,tissue specificity:High levels in peripheral blood leukocytes , pancreas and liver astrocytes. Moderate levels in thymus , spleen and lung. Low levels in placenta , prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders. ,

chemotaxis , defense response , inflammatory response , immune response , cell surface receptor linked signal transduction , G-protein coupled receptor protein signaling pathway , cell-cell signaling , behavior , locomotory behavior ,response to wounding , taxis ,

Secreted.