Total Oct-2 Cell-Based Colorimetric ELISA Kit
-KA3342C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
Oct-2 Rabbit pAb
YT3231
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ELISA Kits
Total Oct-2 Cell-Based Colorimetric ELISA Kit
KA3342C
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抗原&靶点信息
基因名称:
POU2F2
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别名:
POU domain, class 2, transcription factor 2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
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背景:
function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
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功能:
transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, immune response, humoral immune response, RNA biosynthetic process, regulation of transcription, regulation of RNA metabolic process,
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细胞定位:
Cytoplasm . Nucleus.
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组织表达:
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
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