Total MMP-7 Cell-Based Colorimetric ELISA Kit
-KA3333C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
MMP7
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别名:
Matrilysin ;
Matrin ;
Matrix metalloproteinase-7 ;
MMP-7 ;
Pump-1 protease ;
Uterine metalloproteinase ;
Matrin ;
Matrix metalloproteinase-7 ;
MMP-7 ;
Pump-1 protease ;
Uterine metalloproteinase ;
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背景:
catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,
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功能:
proteolysis, collagen catabolic process, collagen metabolic process, regulation of cell proliferation, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
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细胞定位:
Secreted, extracellular space, extracellular matrix .
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