Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CTGF

Connective tissue growth factor

CTGF ;
CCN2 ;
HCS24 ;
IGFBP8 ;
Connective tissue growth factor ;
CCN family member 2 ;
Hypertrophic chondrocyte-specific protein 24 ;
Insulin-like growth factor-binding protein 8 ;
IBP-8 ;
IGF-binding protein 8 ;
IGFBP-8

function:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts , myofibroblasts , endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. ,similarity:Belongs to the CCN family. ,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain. ,similarity:Contains 1 IGFBP N-terminal domain. ,similarity:Contains 1 TSP type-1 domain. ,similarity:Contains 1 VWFC domain. ,subunit:Monomer. ,

skeletal system development , cartilage condensation , ossification , angiogenesis , regulation of cell growth , blood vessel development , vasculature development , DNA metabolic process , DNA replication , cell motion , cell adhesion , cell-matrix adhesion , cell surface receptor linked signal transduction , enzyme linked receptor protein signaling pathway ,transmembrane receptor protein tyrosine kinase signaling pathway , integrin-mediated signaling pathway , intracellular signaling cascade , ectoderm development , fibroblast growth factor receptor signaling pathway , epidermis development , response to wounding , cell-cell adhesion , cell migration , biological adhesion , respiratory tube development , lung development , cell-substrate adhesion , tube development , regulation of growth , blood vessel morphogenesis , skeletal system morphogenesis , cell motility , cartilage development , localization of cell , bone development , respiratory system development ,

Secreted , extracellular space , extracellular matrix . Secreted .