Total MMP-3 Cell-Based Colorimetric ELISA Kit
-KA3332C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
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YT4465
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YC0066
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ELISA Kits
Human MMP-3 ELISA Kit
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ELISA Kits
Total MMP-3 Cell-Based Colorimetric ELISA Kit
KA3332C
预览→
抗原&靶点信息
基因名称:
MMP3
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别名:
Stromelysin-1 ;
SL-1 ;
Matrix metalloproteinase-3 ;
MMP-3 ;
Transin-1 ;
SL-1 ;
Matrix metalloproteinase-3 ;
MMP-3 ;
Transin-1 ;
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背景:
catalytic activity:Preferential cleavage where P1', P2' and P3' are hydrophobic residues.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 4 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
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功能:
response to acid, proteolysis, response to endogenous stimulus, response to organic substance, response to organic nitrogen, response to amine stimulus, collagen catabolic process, collagen metabolic process, response to cytokine stimulus, response to amino acid stimulus, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
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细胞定位:
Secreted, extracellular space, extracellular matrix .
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信号通路
Organismal Systems >> Immune system >> IL-17 signaling pathway
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Prostate cancer
Human Diseases >> Immune disease >> Rheumatoid arthritis
Environmental Information Processing >> Signal transduction >> TNF signaling pathway
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