Total Ki-67 Cell-Based Colorimetric ELISA Kit
-KA3311C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
Ki-67 Rabbit pAb
YT2467
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ELISA Kits
Total Ki-67 Cell-Based Colorimetric ELISA Kit
KA3311C
预览→
抗原&靶点信息
基因名称:
MKI67
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别名:
Antigen KI-67
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背景:
developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,
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功能:
M phase, cell cycle, meiosis, cell proliferation, cell cycle process, cell cycle phase, meiotic cell cycle, M phase of meiotic cell cycle,
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细胞定位:
Chromosome . Nucleus . Nucleus, nucleolus . Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226). Associates with satellite DNA in G1 phase (PubMed:9510506). Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubMed:15896774, PubMed:22002106). Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix (PubMed:22002106). .
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