Total GCS-β-1 Cell-Based Colorimetric ELISA Kit
-KA3285C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
GUCY1B3
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别名:
Guanylate cyclase soluble subunit beta-1 ;
GCS-beta-1 ;
Guanylate cyclase soluble subunit beta-3 ;
GCS-beta-3 ;
Soluble guanylate cyclase small subunit ;
GCS-beta-1 ;
Guanylate cyclase soluble subunit beta-3 ;
GCS-beta-3 ;
Soluble guanylate cyclase small subunit ;
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背景:
catalytic activity:GTP = 3',5'-cyclic GMP + diphosphate.,cofactor:Binds 1 or 2 heme groups per heterodimer.,enzyme regulation:Activated by nitric oxide in the presence of magnesium or manganese ions.,miscellaneous:There are two types of guanylate cyclases: soluble forms and membrane-associated receptor forms.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 1 guanylate cyclase domain.,subunit:Heterodimer of an alpha and a beta chain.,
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功能:
circulatory system process, purine nucleotide metabolic process, purine nucleotide biosynthetic process, cGMP biosynthetic process, intracellular signaling cascade, nitric oxide mediated signal transduction, blood circulation,nucleoside monophosphate metabolic process, nucleoside monophosphate biosynthetic process, nucleotide biosynthetic process, cyclic nucleotide metabolic process, cyclic nucleotide biosynthetic process, nucleobase, nucleoside and nucleotide biosynthetic process, nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process, nitrogen compound biosynthetic process, cGMP metabolic process,
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细胞定位:
Cytoplasm .
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组织表达:
Detected in brain cortex and cerebellum (at protein level).
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Gap junction
Organismal Systems >> Immune system >> Platelet activation
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
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