Total GANP Cell-Based Colorimetric ELISA Kit
-KA3271C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
MCM3AP
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别名:
80 kDa MCM3-associated protein ;
Protein GANP ;
Protein GANP ;
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背景:
function:May be involved in the nuclear localization pathway of MCM3.,similarity:Belongs to the SAC3 family.,subunit:Interacts with MCM3.,
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功能:
DNA metabolic process, DNA replication, protein targeting, protein import into nucleus, intracellular protein transport,nucleocytoplasmic transport, protein localization, protein transport, protein import, protein localization in organelle,protein localization in nucleus, cellular protein localization, establishment of protein localization, intracellular transport,nuclear transport, nuclear import, cellular macromolecule localization,
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细胞定位:
[Isoform GANP]: Nucleus envelope . Nucleus, nuclear pore complex . Nucleus, nucleoplasm . Chromosome . Predominantly located at the nuclear envelope, facing the nucleus interior (PubMed:20005110, PubMed:21195085, PubMed:23591820). Localization at the nuclear pore complex requires NUP153, TPR and ALYREF/ALY (PubMed:23591820, PubMed:22307388). Also found associated with chromatin (PubMed:23652018). In B-cells, targeted to the immunoglobulin variable region genes (PubMed:23652018). .; [Isoform MCM3AP]: Cytoplasm . Nucleus . Translocates into the nucleus in the presence of MCM3 (PubMed:12226073). Associates with chromatin possibly through interaction with MCM3 (PubMed:12226073). .
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组织表达:
Widely expressed (PubMed:11024281). Up-regulated in germinal center B-cells in tonsils (at protein level) (PubMed:11024281).
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