Total GFRα-1 Cell-Based Colorimetric ELISA Kit
-KA3267C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
GFRA1
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别名:
GDNF family receptor alpha-1 ;
GDNF receptor alpha-1 ;
GDNFR-alpha-1 ;
GFR-alpha-1 ;
RET ligand 1 ;
TGF-beta-related neurotrophic factor receptor 1 ;
GDNF receptor alpha-1 ;
GDNFR-alpha-1 ;
GFR-alpha-1 ;
RET ligand 1 ;
TGF-beta-related neurotrophic factor receptor 1 ;
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背景:
function:Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.,similarity:Belongs to the GDNFR family.,subunit:2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.,
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功能:
cell surface receptor linked signal transduction,
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细胞定位:
Cell membrane ; Lipid-anchor, GPI-anchor . Golgi apparatus, trans-Golgi network . Endosome . Endosome, multivesicular body . Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and multivesicular bodies. .
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