Total Fli-1 Cell-Based Colorimetric ELISA Kit
-KA3263C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
FLI1
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别名:
Friend leukemia integration 1 transcription factor ;
Proto-oncogene Fli-1 ;
Transcription factor ERGB ;
Proto-oncogene Fli-1 ;
Transcription factor ERGB ;
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背景:
disease:A chromosomal aberration involving FLI1 is a cause of Ewing sarcoma [MIM:133450]. Translocation t(11;22)(q24;q12) with EWS.,function:Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.,miscellaneous:Located on a fragment of chromosome 11 flanked on the centromeric side by the acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation breakpoint and on the telomeric side by the Ewing- and neuroepithelioma-associated t(11;22) (q24;q12) breakpoint.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,similarity:Contains 1 PNT (pointed) domain.,subunit:Can form homodimers or heterodimers with ETV6/TEL1.,
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功能:
circulatory system process, transcription, regulation of transcription, DNA-dependent, hemostasis, blood circulation,regulation of transcription, regulation of body fluid levels, regulation of RNA metabolic process,
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细胞定位:
Nucleus .
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