Total Cyclin G Cell-Based Colorimetric ELISA Kit
-KA3240C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
CCNG1
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别名:
Cyclin-G1 ;
Cyclin-G ;
Cyclin-G ;
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背景:
developmental stage:Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.,function:May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.,induction:Activated in breast and prostate cancer cells. Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,subcellular location:DNA replication foci after DNA damage.,tissue specificity:High levels in skeletal muscle, ovary, kidney and colon.,
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功能:
regulation of cyclin-dependent protein kinase activity, M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, cell cycle, mitosis, regulation of cell size, cell growth, regulation of phosphate metabolic process, cell cycle process, cell cycle phase, regulation of cellular component size, growth, regulation of phosphorylation, regulation of kinase activity, regulation of protein kinase activity, organelle fission, regulation of phosphorus metabolic process, cell division, regulation of transferase activity, regulation of cell cycle,
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细胞定位:
Nucleus . DNA replication foci after DNA damage.
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组织表达:
High levels in skeletal muscle, ovary, kidney and colon.
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信号通路
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