CDH1

Cadherin-1 ;
CAM 120/80 ;
Epithelial cadherin ;
E-cadherin ;
Uvomorulin ;
CD antigen CD324 ;
[Cleaved into: E-Cad/CTF1 ;
E-Cad/CTF2 ;
E-Cad/CTF3]

in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation,protein complex assembly, cell adhesion, homophilic cell adhesion, synaptogenesis, response to toxin, embryonic development ending in birth or egg hatching, response to organic substance, regulation of cell death, cell-cell adhesion, diencephalon development, pituitary gland development, biological adhesion, cell projection organization,neuron differentiation, forebrain development, neuron projection development, regulation of intracellular transport,positive regulation of intracellular transport, regulation of protein localization, regulation of intracellular protein transport, endocrine system development, regulation of protein import into nucleus, positive regulation of protein import into nucleus, response to drug, regulation of apoptosis, regulation of transcription factor import into nucleus,positive regulation of transcription factor import into nucleus, chordate embryonic development, extracellular structure organization, regulation of programmed cell death, regulation of caspase activity, macromolecular complex subunit organization, regulation of nucleocytoplasmic transport, positive regulation of nucleocytoplasmic transport, neuron development, gland development, synapse organization, positive regulation of transport, positive regulation of protein transport, regulation of protein transport, protein oligomerization, protein homooligomerization, regulation of hydrolase activity, regulation of peptidase activity, regulation of endopeptidase activity, regulation of cellular localization, macromolecular complex assembly, regulation of establishment of protein localization, protein complex biogenesis,

Cell junction, adherens junction . Cell membrane ; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.

Non-neural epithelial tissues.