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Total Cytokeratin 8 Cell-Based Colorimetric ELISA Kit

-KA3140C

主要信息
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification

Unmodified

货号: KA3140C
规格
价格
货期
数量
96well
¥3,300.00
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详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
KRT8
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别名:
Keratin, type II cytoskeletal 8 ;
Cytokeratin-8 ;
CK-8 ;
Keratin-8 ;
K8 ;
Type-II keratin Kb8 ;
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数据库链接:
Organism 基因 ID SwissProt
Human 3856; P05787;
Mouse 16691; P11679;
Rat 25626; Q10758;
背景:
keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
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功能:
apoptosis, cytoskeleton organization, cell death, programmed cell death, death, cytokine-mediated signaling pathway,tumor necrosis factor-mediated signaling pathway,
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细胞定位:
Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .
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组织表达:
Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
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货号: KA3140C
规格
价格
货期
数量
96well
¥3,300.00
两周

0

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已收藏

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