GAB1

GRB2-associated-binding protein 1 ;
GRB2-associated binder 1 ;
Growth factor receptor bound protein 2-associated protein 1 ;

function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,

MAPKKK cascade, activation of MAPK activity, regulation of protein amino acid phosphorylation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, response to oxidative stress, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signaling cascade, protein kinase cascade, JNK cascade, activation of JUN kinase activity, cell proliferation, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, response to organic substance, regulation of protein kinase cascade, phosphorylation, regulation of phosphate metabolic process,regulation of cell migration, stress-activated protein kinase signaling pathway, regulation of protein modification process, regulation of cellular protein metabolic process, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus, cellular response to stress, positive regulation of kinase activity,regulation of locomotion, regulation of phosphorylation, positive regulation of catalytic activity, regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of MAPKKK cascade, response to peptide hormone stimulus, regulation of JUN kinase activity, positive regulation of JUN kinase activity, regulation of kinase activity,positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, regulation of JNK cascade, regulation of phosphorus metabolic process, regulation of cell motion, regulation of transferase activity, positive regulation of transferase activity, regulation of stress-activated protein kinase signaling pathway, regulation of cellular response to stress,