Casein Kinase I α (Phospho Tyr321) Cell-Based Colorimetric ELISA Kit
-KA1528C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
Casein Kinase Iα Rabbit pAb
YT0645
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Primary Antibodies
Casein Kinase Iα (Phospho Thr321) Rabbit pAb
YP0392
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ELISA Kits
Total Casein Kinase Iα Cell-Based Colorimetric ELISA Kit
KA3615C
预览→
ELISA Kits
Casein Kinase I α (Phospho Tyr321) Cell-Based Colorimetric ELISA Kit
KA1528C
预览→
抗原&靶点信息
基因名称:
CSNK1A1
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别名:
Casein kinase I isoform alpha ;
CKI-alpha ;
CK1 ;
CKI-alpha ;
CK1 ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,
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功能:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, phosphorylation,
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细胞定位:
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Nucleus speckle . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). .
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信号通路
Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Human Diseases >> Cancer: specific types >> Gastric cancer
Human Diseases >> Cancer: specific types >> Breast cancer
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway
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