CD226

CD226 antigen ;
DNAX accessory molecule 1 ;
DNAM-1 ;
CD antigen CD226 ;

function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with PVR and PVRL2.,tissue specificity:Expressed by peripheral blood T-lymphocytes.,

cytokine production, regulation of leukocyte mediated cytotoxicity, positive regulation of leukocyte mediated cytotoxicity, positive regulation of immune system process, regulation of leukocyte activation, positive regulation of leukocyte activation, regulation of immune effector process, positive regulation of immune effector process, regulation of leukocyte mediated immunity, positive regulation of leukocyte mediated immunity, regulation of lymphocyte mediated immunity, positive regulation of lymphocyte mediated immunity, regulation of B cell mediated immunity,positive regulation of B cell mediated immunity, regulation of natural killer cell mediated immunity, positive regulation of natural killer cell mediated immunity, regulation of adaptive immune response, positive regulation of adaptive immune response, regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, regulation of response to biotic stimulus, positive regulation of response to biotic stimulus, regulation of response to tumor cell, positive regulation of response to tumor cell, regulation of immune response to tumor cell, positive regulation of immune response to tumor cell, regulation of natural killer cell mediated immune response to tumor cell, positive regulation of natural killer cell mediated immune response to tumor cell, regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immunoglobulin mediated immune response, positive regulation of immunoglobulin mediated immune response, cell adhesion, cell recognition, positive regulation of signal transduction, positive regulation of cell communication,biological adhesion, regulation of cell killing, positive regulation of cell killing, positive regulation of defense response,regulation of mast cell activation, positive regulation of mast cell activation, regulation of natural killer cell mediated cytotoxicity, regulation of innate immune response, positive regulation of innate immune response, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of response to stimulus, positive regulation of immune response, regulation of cell activation, positive regulation of cell activation, regulation of Fc receptor mediated stimulatory signaling pathway, positive regulation of Fc receptor mediated stimulatory signaling pathway,

Cell membrane ; Single-pass type I membrane protein .

Expressed by peripheral blood T-lymphocytes.