MYPT1 (Phospho Thr853) Cell-Based Colorimetric ELISA Kit
-KA1305C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
MYPT1 Rabbit pAb
YT2955
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Primary Antibodies
MYPT1 (Phospho Thr696) Rabbit pAb
YP1131
预览→
Primary Antibodies
MYPT1 (Phospho Thr853) Rabbit pAb
YP0662
预览→
ELISA Kits
Total MYPT1 Cell-Based Colorimetric ELISA Kit
KA4192C
预览→
ELISA Kits
MYPT1 (Phospho Thr853) Cell-Based Colorimetric ELISA Kit
KA1305C
预览→
抗原&靶点信息
基因名称:
PPP1R12A
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别名:
Protein phosphatase 1 regulatory subunit 12A ;
Myosin phosphatase-targeting subunit 1 ;
Myosin phosphatase target subunit 1 ;
Protein phosphatase myosin-binding subunit ;
Myosin phosphatase-targeting subunit 1 ;
Myosin phosphatase target subunit 1 ;
Protein phosphatase myosin-binding subunit ;
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背景:
function:Regulates myosin phosphatase activity.,PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity). Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 6 ANK repeats.,subcellular location:Along actomyosin filaments and stress fibers.,subunit:PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity). Binds PPP1R12B, ROCK1 and IL16.,
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细胞定位:
Cytoplasm . Cytoplasm, cytoskeleton, stress fiber . Also along actomyosin filaments. .
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组织表达:
Expressed in striated muscles, specifically in type 2a fibers (at protein level).
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton
Organismal Systems >> Immune system >> Platelet activation
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
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