CD19 (Phospho Tyr531) Cell-Based Colorimetric ELISA Kit
-KA1238C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
CD19 Rabbit pAb
YT5580
预览→
Primary Antibodies
CD19 (Phospho Tyr531) Rabbit pAb
YP0295
预览→
ELISA Kits
Total CD19 Cell-Based Colorimetric ELISA Kit
KA4028C
预览→
ELISA Kits
CD19 (Phospho Tyr531) Cell-Based Colorimetric ELISA Kit
KA1238C
预览→
抗原&靶点信息
基因名称:
CD19
展开内容
别名:
B-lymphocyte antigen CD19 ;
B-lymphocyte surface antigen B4 ;
Differentiation antigen CD19 ;
T-cell surface antigen Leu-12 ;
CD antigen CD19 ;
B-lymphocyte surface antigen B4 ;
Differentiation antigen CD19 ;
T-cell surface antigen Leu-12 ;
CD antigen CD19 ;
展开内容
背景:
disease:Defects in CD19 are a cause of hypogammaglobulinemia [MIM:107265].,function:Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.,online information:CD19 mutation db,PTM:Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. Interacts with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. Interacts with PLCG2 when phosphorylated on Tyr-409.,
展开内容
功能:
activation of immune response, immune response-activating cell surface receptor signaling pathway, positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, defense response, cellular defense response, cell surface receptor linked signal transduction, positive regulation of response to stimulus, positive regulation of immune response, antigen receptor-mediated signaling pathway, B cell receptor signaling pathway,
展开内容
细胞定位:
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
展开内容
组织表达:
Detected on marginal zone and germinal center B cells in lymph nodes (PubMed:2463100). Detected on blood B cells (at protein level) (PubMed:2463100, PubMed:16672701).
展开内容
信号通路
文献引用（{{totalcount}}）
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}