SRF

Serum response factor ;
SRF ;

function:SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentation and maturation.,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 MADS-box domain.,subunit:Binds DNA as a multimer, probably a dimer. Interacts with MLLT7/FOXO4, NKX3A and SSRP1. Interacts with ARID2 and SRFBP1 (By similarity). Forms complexes with ARID2, MYOCD, NKX2-5 and SRFBP1.,

angiogenesis, blood vessel development, in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation, vasculature development, heart looping, sprouting angiogenesis, cell migration during sprouting angiogenesis, heart morphogenesis, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell motion, regulation of muscle contraction,regulation of smooth muscle contraction, heart development, aging, response to wounding, response to toxin,response to endogenous stimulus, response to hormone stimulus, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, response to organic substance, senescence, regulation of specific transcription from RNA polymerase II promoter, positive regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, positive regulation of transcription via serum response element binding, cell migration, cellular homeostasis, neuron differentiation, positive regulation of cellular biosynthetic process, positive regulation of protein complex assembly, regulation of gene-specific transcription,response to cytokine stimulus, tube morphogenesis, tube development, wound healing, homeostatic process,chordate embryonic development, positive regulation of gene-specific transcription, regulation of protein complex assembly, blood vessel endothelial cell migration, endothelial cell migration, regulation of system process, regulation of cellular component biogenesis, regulation of transcription, positive regulation of cell differentiation, positive regulation of transcription, DNA-dependent, positive regulation of muscle contraction, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, positive regulation of smooth muscle contraction, muscle maintenance, blood vessel morphogenesis, neuron development, cell motility, positive regulation of developmental process, positive regulation of cellular component organization, regulation of muscle cell differentiation, regulation of smooth muscle cell differentiation, positive regulation of nitrogen compound metabolic process, positive regulation of multicellular organismal process, regulation of RNA metabolic process, positive regulation of RNA metabolic process,localization of cell, angiogenesis involved in wound healing, anatomical structure homeostasis, regulation of transcription initiation from RNA polymerase II promoter, positive regulation of transcription initiation from RNA polymerase II promoter,

Nucleus .