Csk (Phospho Tyr304) Rabbit pAb
-YP1858
主要信息
Target
Csk Phospho Tyr304
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, WB
MW
55kD (Observed)
Conjugate/Modification
Phospho
货号: YP1858
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Csk (Phospho Tyr304) Rabbit pAb at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MEyLE
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
55kD
修饰
Phospho
克隆性
Polyclonal
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Csk (Phospho Tyr304)
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特异性:
This antibody detects endogenous levels of Csk (Phospho Tyr304) Rabbit pAb at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MEyLE
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基因名称:
CSK
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蛋白名称:
Tyrosine-protein kinase CSK (C-Src kinase) (Protein-tyrosine kinase CYL)
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别名:
Tyrosine-protein kinase CSK ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
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功能:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,Function:Specifically phosphorylates 'Tyr-504' on LCK , which acts as a negative regulatory site. Can also act on the LYN and FYN kinases. ,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 1 SH2 domain. ,similarity:Contains 1 SH3 domain. ,subcellular location:Mainly cytoplasmic , also present in lipid rafts. ,subunit:Interacts with PTPN8 (By similarity) . Interacts with phosphorylated SIT1 , PAG1 , LIME1 and TGFB1I1. ,tissue specificity:Expressed in lung and macrophages. ,
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细胞定位:
Cytoplasm . Cell membrane . Mainly cytoplasmic , also present in lipid rafts. .
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组织表达:
研究领域:
>>Epithelial cell signaling in Helicobacter pylori infection
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货号: YP1858
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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