Mouse BDNF(Brain Derived Neurotrophic Factor) ELISA Kit
-KE1274
主要信息
Reactivity
Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
货号: KE1274
规格
价格
货期
数量
5*96well
￥11,000.00
两周
0
2*96well
￥4,500.00
两周
0
96well
￥2,350.00
两周
0
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详细信息
特异性
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
储存
2-8°C/6 months,Ship by ice bag
修饰
Unmodified
样本类型
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
检测方法
Colorimetric
检测范围
31.25--2000pg/mL
灵敏度
18.75pg/mL
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抗原&靶点信息
特异性:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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基因名称:
BDNF
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蛋白名称:
BDNF(Brain Derived Neurotrophic Factor)
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别名:
Brain-derived neurotrophic factor ;
BDNF ;
Abrineurin ;
BDNF ;
Abrineurin ;
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背景:
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
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功能:
Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678).
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability
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细胞定位:
Secreted .; [BDNF precursor form]: Secreted . A proportion of BDNF is secreted as immature precursor (proBDNF). .
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信号通路
Organismal Systems >> Nervous system >> Neurotrophin signaling pathway
Human Diseases >> Neurodegenerative disease >> Huntington disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
文献引用（{{totalcount}}）
货号: KE1274
规格
价格
货期
数量
5*96well
￥11,000.00
两周
0
2*96well
￥4,500.00
两周
0
96well
￥2,350.00
两周
0
加入购物车
已收藏
收藏
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