Function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. ,similarity:Belongs to the synaptobrevin family. ,similarity:Contains 1 v-SNARE coiled-coil homology domain. ,subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG) . Not found on the mature secretory organelles. ,subunit:Identified in a complex containing STX6 , STX13 , VAMP4 and VTI1A. ,
展开内容