CUX1 (Phospho Ser1215) Rabbit pAb
-YP1769
主要信息
Target
CUX1 Phospho Ser1215
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
166kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1769
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of CUTL1 (Phospho-Ser1215) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RHsSV
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
166kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
抗原&靶点信息
免疫原:
Synthesized peptide derived from human CUTL1 (Phospho-Ser1215)
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特异性:
This antibody detects endogenous levels of CUTL1 (Phospho-Ser1215) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RHsSV
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基因名称:
CUX1 CUTL1
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蛋白名称:
Homeobox protein cut-like 1 (Phospho-Ser1215)
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别名:
Homeobox protein cut-like 1 ;
CCAAT displacement protein ;
CDP ;
Homeobox protein cux-1 ;
CCAAT displacement protein ;
CDP ;
Homeobox protein cux-1 ;
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背景:
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression , morphogenesis , and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq , Feb 2011] ,
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功能:
Alternative products:Additional isoforms seem to exist ,Function:May be involved in intra-Golgi retrograde transport. ,Function:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta , an ATC-rich DNA sequence located upstream of the TCR beta enhancer. ,miscellaneous:Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization. ,PTM:Phosphorylated upon DNA damage , probably by ATM or ATR. ,similarity:Belongs to the CASP family. ,similarity:Belongs to the CUT homeobox family. ,similarity:Contains 1 homeobox DNA-binding domain. ,similarity:Contains 3 CUT DNA-binding domains. ,subunit:Homodimer; disulfide-linked. Interacts with GOLGA5. ,subunit:Interacts with BANP. ,
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细胞定位:
Nucleus .
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组织表达:
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货号: YP1769
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
已收藏
收藏
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