USF1 (Phospho Thr153) Rabbit pAb
-YP1746
主要信息
Target
USF1 Phospho Thr153
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
34kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1746
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of USF1 (Phospho-Thr153) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QAtPP
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
34kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
抗原&靶点信息
免疫原:
Synthesized peptide derived from human USF1 (Phospho-Thr153)
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特异性:
This antibody detects endogenous levels of USF1 (Phospho-Thr153) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QAtPP
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基因名称:
USF1 BHLHB11 USF
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蛋白名称:
USF1 (Phospho-Thr153)
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别名:
Upstream stimulatory factor 1 ;
Class B basic helix-loop-helix protein 11 ;
bHLHb11 ;
Major late transcription factor 1 ;
Class B basic helix-loop-helix protein 11 ;
bHLHb11 ;
Major late transcription factor 1 ;
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背景:
This gene encodes a member of the basic helix-loop-helix leucine zipper family , and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL) . Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq , Feb 2013] ,
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功能:
Disease:Genetic variations in USF1 are associated with combined hyperlipidemia type 1 (HYPLIP1) [MIM:602491]; also known as familial combined hyperlipidemia type 1 (FCHL1) . HYPLIP1 is characterized by elevated levels of serum total cholesterol , triglycerides or both , and is observed in about 20% of individuals with premature coronary heart disease. ,Function:Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. ,similarity:Contains 1 basic helix-loop-helix (bHLH) domain. ,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2) . Interacts with varicella-zoster virus IE62 protein. ,
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细胞定位:
Nucleus.
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组织表达:
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文献引用（{{totalcount}}）
货号: YP1746
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
已收藏
收藏
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