The antiserum was produced against synthesized Acetyl-peptide derived from human HSP90A/B around the Acetylation site of Lys292/284. AA range:251-300

This antibody detects endogenous levels of HSP 90 only when acetylated at Human:K292/284, Mouse:K293/284, Rat:K293/284.This antibody does not recognize acetylated at other sites.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LNkTK

HSP90AA1/HSP90AB1

Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta

HSP90AA1 ;
HSP90A ;
HSPC1 ;
HSPCA ;
Heat shock protein HSP 90-alpha ;
Heat shock 86 kDa ;
HSP 86 ;
HSP86 ;
Renal carcinoma antigen NY-REN-38 ;
HSP90AB1 ;
HSP90B ;
HSPC2 ;
HSPCB ;
Heat shock protein HSP 90-beta ;
HSP 90 ;
Heat shock 84 kDa ;
HSP 84 ;
HSP84

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,Function:Molecular chaperone.,Function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,

Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

>>Protein processing in endoplasmic reticulum ;
>>PI3K-Akt signaling pathway ;
>>Necroptosis ;
>>Antigen processing and presentation ;
>>NOD-like receptor signaling pathway ;
>>IL-17 signaling pathway ;
>>Th17 cell differentiation ;
>>Progesterone-mediated oocyte maturation ;
>>Estrogen signaling pathway ;
>>Salmonella infection ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Prostate cancer ;
>>Lipid and atherosclerosis ;
>>Fluid shear stress and atherosclerosis